Senior Scientist, TCR Therapy

Gaithersburg, US   |   full time   |   Job ID: 11079 

About the role:

Join our pioneering team in Gaithersburg, MD, as a Senior Scientist dedicated to advancing personalized TCR therapies targeting patient-specific cancer antigens for solid tumors. In this impactful role, you will lead cutting-edge scientific initiatives to refine our TCR platform and translate it into scalable clinical therapies, directly contributing to BioNTech's mission of transforming patient outcomes through innovative immunotherapy solutions.

You will thrive in a collaborative and dynamic environment that values scientific rigor and innovation. As part of a global network of experts, your contributions will shape the future of personalized therapies and make a meaningful difference in patients' lives.

Your contribution:

Design and execute studies to enhance our TCR platform, focusing on multiplexed TCR delivery meeting safety, efficacy, and scalability standards
Establish, optimize, and troubleshoot high-throughput workflows supporting discovery, screening, and validation activities
Drive innovation by adopting novel technologies and methodologies aligned with evolving scientific and clinical needs
Lead cross-site and cross-functional collaborations to ensure timely delivery of project milestones
Mentor team members while fostering a high-performance culture and professional development
Communicate findings effectively through tailored presentations for executive and technical audiences

A good match:

PhD in Immunology, Biomedical Sciences, or related field with deep expertise in tumor immunology or TCR/neoantigen biology
Proficiency in immunological techniques such as T cell functional assays, FACS analysis, IncuCyte assays, and cell line engineering
Advanced computational skills (Python/R) with knowledge of AI/ML applications in immunology or experience collaborating with AI/ML teams
Strong organizational skills with meticulous experimental documentation
Proven ability to excel in fast-paced environments while adapting to evolving priorities

Preferred requirements: experience with personalized immunotherapies or spatial biology approaches like spatial transcriptomics

US based candidates expected Pay Range: $113,600 - $181,600/year + benefits, annual bonus & equity (bonus and equity is variable and dependent on company and individual performance). *Compensation for the role will depend on several factors, including responsibilities of the job, education, experience, knowledge, skills, and abilities.

Your Benefits

BioNTech US is committed to employee wellbeing and offers best-in-class benefits & HR programs to support an inclusive & diverse workforce. Salaried/Position-Targeted Hourly Employees working 30+ hours per week are eligible for our comprehensive benefits package. Benefits include but are not limited to:

• Medical, Dental and Vision Insurance
• Life, AD&D, Critical Illness Insurance
• Pre-tax HSA & FSA, DCRA Spending Accounts
• Employee Assistance & Concierge Program (EAP) available 24/7
• Parental and Childbirth Leave & Family Planning Assistance
• Sitterstream: Virtual Tutoring & Childcare Membership
• Paid Time Off: Vacation, Sick, Bereavement, Holidays (including Floating) & Year-End U.S. Shutdown.
• 401(K) Plan with Company Match
• Tuition Reimbursement & Student Loan Assistance Programs
• Wellbeing Incentive Platforms & Incentives
• Professional Development Programs
• Commuting Allowance and subsidized parking
• Discounted Home, Auto & Pet Insurance

…and more! More details to be shared.
 

Located in the BioHealth Capital Region near Washington DC and ranked among the top biopharma hubs in the country, Gaithersburg, Maryland offers a unique and diverse cluster across industry, government, and academia for top talent and scientific innovation. As a pivotal player within the life sciences community, Gaithersburg is distinguished by its robust infrastructure and strategic location near the nation’s capital. The city’s strategic significance is amplified by its state-of-the-art manufacturing facilities that cater to the rigorous demands of the life sciences industry; Gaithersburg’s manufacturing sector is defined by advanced technologies and complies with the most stringent regulatory standards, ensuring the production of high-quality pharmaceuticals, biologics, and medical devices. In the coming years, Gaithersburg will continue to be a vital contributor to the future of medical science and technology.

Apply now - We look forward to your application!

Apply for our Gaithersburg, US location and simply send us your documents using our online form.

By submitting your application, you acknowledge that a background check will be conducted as part of the recruitment process in accordance with applicable laws and regulations. If you are considered for the position, BioNTech will conduct the background check through our service provider ‘HireRight’. You will be informed accordingly by your BioNTech-Recruiter.