Senior Research Associate

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Based in Cambridge, MA and Gaithersburg, MD. We are committed to improving the health of people worldwide with our fundamental research and our work in the area of development of immunotherapies utilizing the full potential of the immune system to fight cancer, infectious diseases and other serious diseases. We believe in scientific rigor, innovation and passion as driving forces. BioNTech was founded by scientists and physicians to translate science into survival by combining fundamental research and operational excellence.

With decades of deep immunology expertise and experience in developing and optimizing mRNA as part of its broad suite of novel technologies, the company is working with the global community to defeat life-threatening and serious diseases such as cancer, COVID-19, malaria and tuberculosis. The first ever approved mRNA vaccine was created in the labs of BioNTech in Mainz, Germany. A fully integrated immunotherapy powerhouse. We remain focused on bringing our broad pipeline of next-generation immunotherapies and vaccines to people around the world to address cancer, infectious diseases, as well as a growing list of other medical conditions. To accomplish this, we continue to be deeply rooted in science and academic research while also having built a fully integrated, global immunotherapy company with cGMP and GMP manufacturing facilities anchored around deep expertise in immunology and complemented by an expanding set of capabilities.



Senior Research Associate 


We are seeking a highly motivated Senior Research Associate to join BioNTech’s Center of Excellence in Cell & Gene Therapy Research, Process & Analytical Development and Manufacturing facility in Gaithersburg, MD. You will be part of the multi-disciplinary Research team focused on developing TCR-T cell therapies targeting solid tumors. In this role, the SRA will have the opportunity to assist in the validation and characterization of novel TCRs for cell therapy, as well as participate in cross-functional collaborations across the company.


Primary responsibilities include:

  • Perform isolation, activation, and multi-parametric characterization of resulting immune cell products using a variety of characterization techniques
  • Optimizing and conducting experiments to support TCR validation and characterization efforts
  • Develop systems for TCR efficacy testing, including organoids and cell line engineering
  • Perform viral vector-based or electroporation-based modification of primary immune cells and various cell lines.
  • Support development of enhancement and delivery strategies for cell therapy products
  • Record experimental procedures and results in an organized and timely manner; disseminate/present findings to internal groups and cross-site functional groups in a professional manner
  • Assist in general lab organization within the team, and lab inventory.


  • BS or MS degree in sciences and 2-5 years of relevant experience in biology or immunology in a research lab setting.
  • Aseptic cell culture experience including primary cells and various cell lines
  • Expertise in immunological techniques including isolation and activation of T cells, functional assays, cytotoxic killing assay using FACS, MSD, xCELLigence and other methods
  • Proficiency in the use of software to support data analysis such as FlowJo, FACSDiva, GraphPad Prism, as well as Microsoft Office (Excel, PowerPoint, Word, Outlook)Strong attention to detail
  • Excellent communication, teamwork, and organizational skills
  • Independent, flexible, self-motivated, and the ability to work well with others


Preferred Requirements:

  • A strong interest in T cell biology and cancer immunotherapy
  • A strong desire to learn high-throughput assay development via automation



Benefits for you:


BioNTech US is committed to the well being of our team members and offers a variety of benefits supporting our diverse employee base. Salaried/Position-Targeted Hourly Employees working 30+ hours per week are eligible for our comprehensive benefits package. Benefits include but are not limited to:

  • Medical, Dental and Vision Insurance

  • Life, AD&D, STD and LTD Insurance

  • HSA & FSA Spending Accounts

  • Health & Wellness, including free onsite gym access

  • Adoption & Surrogacy Assistance

  • Vacation and Unlimited Sick Time

  • Holidays and Floating Holidays, including discretionary winter shutdown

  • 401(K) Plan with Significant Company Match

  • Tuition Reimbursement and Professional Development

  • Commuting Assistance and subsidized parking

  • Discounted Home and Auto Insurance

  • Pet Insurance

Plus more benefits that will be shared upon hire!



Have we kindled your pioneering spirit?


Then apply now for our location Gaithersburg  and simply send us your application documents using our online form.

BioNTech does not tolerate discrimination, favoritism, or harassment based on gender, political opinion, religion or belief, nationality, ethnic or social origin, age, sexual orientation, marital status, disability, physical appearance, health status or any other aspect of personal status. We are committed to creating a diverse and inclusive environment and are proud to be an equal opportunity employer. Most important – it’s a match!

BioNTech - As unique as you