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Scientist, Cell & Gene Therapy


Join our team of pioneers!

Based in Cambridge, MA and Gaithersburg, MD. We are committed to improving the health of people worldwide with our fundamental research and our work in the area of development of immunotherapies utilizing the full potential of the immune system to fight cancer, infectious diseases and other serious diseases. We believe in scientific rigor, innovation and passion as driving forces. BioNTech was founded by scientists and physicians to translate science into survival by combining fundamental research and operational excellence.

With decades of deep immunology expertise and experience in developing and optimizing mRNA as part of its broad suite of novel technologies, the company is working with the global community to defeat life-threatening and serious diseases such as cancer, COVID-19, malaria and tuberculosis. The first ever approved mRNA vaccine was created in the labs of BioNTech in Mainz, Germany. A fully integrated immunotherapy powerhouse. We remain focused on bringing our broad pipeline of next-generation immunotherapies and vaccines to people around the world to address cancer, infectious diseases, as well as a growing list of other medical conditions. To accomplish this, we continue to be deeply rooted in science and academic research while also having built a fully integrated, global immunotherapy company with cGMP and GMP manufacturing facilities anchored around deep expertise in immunology and complemented by an expanding set of capabilities.

 

 

Scientist, Cell & Gene Therapy 

 

We are seeking a highly passionate and motivated Scientist to join BioNTech’s Center of Excellence in Cell & Gene Therapy Research, Process & Analytical Development and Manufacturing facility in Gaithersburg, MD. You will be part of a multi-disciplinary Research team dedicated to revolutionizing cancer treatment, focusing on developing novel TCR-T cell therapies targeting solid tumors. As a key contributor to our mission, you will be responsible for generating patient-derived tumor organoids to provide critical insights to various cell therapy modalities. This unique opportunity offers you the chance to directly impact the future of cancer treatment, working closely with our expert teams across the US and Germany BioNTech sites in a collaborative, fast-paced environment. 

 

If you're interested in making a tangible difference and be part of a pioneering effort to transform cancer immunotherapy and deliver groundbreaking treatments to patients in need, we encourage you to join our collaborative and innovative team at BioNTech Gaithersburg.

 

Primary Responsibilities

  • Processing of tumor biopsies to generate and culture patient-derived tumor organoids from various cancer indications.
  • Genetic engineering of primary immune cells and patient-derived tumor organoids and perform functional and phenotypic characterization of engineered cells by multi-color flow cytometry and ELISA.
  • Design, optimize and execute cell-based functional assays to evaluate combinations of different immune cells and enhancements in eliminating tumor organoids.
  • Present results to scientific peers, stakeholders, and collaborators in a professional manner.
  • Assist with the training of junior lab personnel to move projects forward.
  • Track and compile results in an electronic notebook.


Requirements: 

  • PhD in Immunology / Biomedical Sciences or a closely related field with 0-4 years of relevant experience
  • Experience in immunological techniques and immunoassays, such as activation of T cells, T cell transduction, flow cytometry, ELISA.
  • Strong verbal and written communication skills in making impactful scientific presentations to a diverse, cross-functional audience.
  • Proactive, self-motivated team player with strong interpersonal skills and an appropriate sense of urgency and the ability to work independently in a fast-paced environment.

 

Preferred Requirements:

  • Experience in liquid handling/automation to carry out high throughput, cell-based assays is a plus. 
  • Experience in working with 3D culture and tumor organoid models.

 

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Benefits for you:
 

BioNTech US is committed to employee wellbeing and offers best-in-class benefits & HR programs to support an inclusive & diverse workforce. Salaried/Position-Targeted Hourly Employees working 30+ hours per week are eligible for our comprehensive benefits package. Benefits include but are not limited to:

  • Medical, Dental and Vision Insurance

  • Life, AD&D, Critical Illness Insurance

  • Pre-tax HSA & FSA, DCRA Spending Accounts

  • Employee Assistance & Concierge Program (EAP) available 24/7

  • Parental and Childbirth Leave & Family Planning Assistance

  • Sitterstream: Virtual Tutoring & Childcare Membership

  • Paid Time Off: Vacation, Sick, Bereavement, Holidays (including Floating) & Year-End U.S. Shutdown.

  • 401(K) Plan with Company Match

  • Tuition Reimbursement & Student Loan Assistance Programs

  • Wellbeing Incentive Platforms & Incentives

  • Professional Development Programs

  • Commuting Allowance and subsidized parking

  • Discounted Home, Auto & Pet Insurance

 

…and more! More details to be shared.


 

BioNTech is an equal opportunity employer and complies with all applicable federal, state, and local fair employment practices laws. BioNTech does not tolerate discrimination against employees or applicants because of race, color, religion, creed, national origin or ancestry, ethnicity, sex (including gender, pregnancy, sexual orientation, and gender identity), age, physical or mental disability, citizenship, past, current, or prospective service in the uniformed services, genetic information, or any other characteristic protected under applicable federal, state, or local law.

If you are unable or limited in your ability to use or access BioNTech’s online application tools due to a disability, you can request reasonable accommodations by calling 1-857-228-6231or by e-mailing jobs@biontech.de. Thank you for your interest in BioNTech.

 

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