Associate Scientist, Cell Therapy

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Based in Cambridge, MA and Gaithersburg, MD. We are committed to improving the health of people worldwide with our fundamental research and our work in the area of development of immunotherapies utilizing the full potential of the immune system to fight cancer, infectious diseases and other serious diseases. We believe in scientific rigor, innovation and passion as driving forces. BioNTech was founded by scientists and physicians to translate science into survival by combining fundamental research and operational excellence.

With decades of deep immunology expertise and experience in developing and optimizing mRNA as part of its broad suite of novel technologies, the company is working with the global community to defeat life-threatening and serious diseases such as cancer, COVID-19, malaria and tuberculosis. The first ever approved mRNA vaccine was created in the labs of BioNTech in Mainz, Germany. A fully integrated immunotherapy powerhouse. We remain focused on bringing our broad pipeline of next-generation immunotherapies and vaccines to people around the world to address cancer, infectious diseases, as well as a growing list of other medical conditions. To accomplish this, we continue to be deeply rooted in science and academic research while also having built a fully integrated, global immunotherapy company with cGMP and GMP manufacturing facilities anchored around deep expertise in immunology and complemented by an expanding set of capabilities.



Associate Scientist, Cell Therapy 


We are seeking a highly motivated Associate Scientist to join BioNTech’s Research, Technical Development, and Manufacturing facility in Gaithersburg, MD. You will be part of the multi-disciplinary Research team focused on developing personalized TCR-T cell therapies targeting solid tumors.


  • Culture primary T cells and cancer cell lines.
  • Design and execute in vitro experiments for TCR screening, validation, and characterization to support TCR immunotherapy product development.
  • Develop and optimize novel tools and/or methods for characterizing TCR functionality to help with lead candidate prioritization.
  • Support mRNA synthesis efforts within the team as needed.
  • Optimize current protocols and processes by incorporating more automation workflows to enhance throughput.
  • Record experimental procedures and results in an ELN and disseminate findings to the rest of the team in a timely and professional manner.



  • Bachelor’s degree with 5-8 years or Master’s degree with 3-5 years of relevant experience in immunology, cell therapy, or closely related field
  • Skilled in aseptic cell culture technique and cultivation of primary human cells
  • Experience with common immunological techniques such as leukopak processing, cell isolation, viral production and cell transduction, T cell activation assays and cytotoxic killing assays
  • Experience in multicolor flow cytometry
  • The ability to think critically and work independently with minimal supervision
  • Excellent verbal/written communication skills and ability to communicate results to a diverse cross-functional audience
  • Ability to collaborate cross-functionally, be comfortable in a fast-paced environment, and embrace change
  • Exceptional organization and attention to detail
  • Proactive, self-motivated team player with strong interpersonal skills


Preferred Requirements:

  • Experience in Molecular Immunology techniques including but not limited to PCR, in vitro transcribed-mRNA production, and RNA purification
  • Experience with automation instrumentation and high-throughput technology including liquid handlers. Strong interest to learn and operate automation equipment is desirable.
  • An understanding of T cell biology and adoptive cell therapy.




Benefits for you:


BioNTech US is committed to the well being of our team members and offers a variety of benefits supporting our diverse employee base. Salaried/Position-Targeted Hourly Employees working 30+ hours per week are eligible for our comprehensive benefits package. Benefits include but are not limited to:

  • Medical, Dental and Vision Insurance

  • Life, AD&D, STD and LTD Insurance

  • HSA & FSA Spending Accounts

  • Health & Wellness, including free onsite gym access

  • Adoption & Surrogacy Assistance

  • Vacation and Unlimited Sick Time

  • Holidays and Floating Holidays, including discretionary winter shutdown

  • 401(K) Plan with Significant Company Match

  • Tuition Reimbursement and Professional Development

  • Commuting Assistance and subsidized parking

  • Discounted Home and Auto Insurance

  • Pet Insurance

Plus more benefits that will be shared upon hire!



Have we kindled your pioneering spirit?


Then apply now for our location Gaithersburg  and simply send us your application documents using our online form.

BioNTech does not tolerate discrimination, favoritism, or harassment based on gender, political opinion, religion or belief, nationality, ethnic or social origin, age, sexual orientation, marital status, disability, physical appearance, health status or any other aspect of personal status. We are committed to creating a diverse and inclusive environment and are proud to be an equal opportunity employer. Most important – it’s a match!

BioNTech - As unique as you