(Senior) Clinical Scientist* Infectious Diseases

(Senior) Clinical Scientist* Infectious Diseases

Become a member of the BioNTech Family!

Based in Cambridge, MA, BioNTech US serves as BioNTech’s North American headquarters and is an important part of our global effort to pioneer the development of next-generation immuno-oncology therapies. BioNTech US is a fully integrated subsidiary with a strong foundation in Europe and a focus on the development of novel neoantigen-targeted T cell therapies, complementing BioNTech’s highly innovative scientific approach and diversified pipeline of transformative cancer medicines. As a key research and clinical development hub, BioNTech US will enable BioNTech’s growing presence in the US.


  • Contribute to the development and creation of clinical trial protocols following high scientific and clinical standards and applicable regulations. Also contribute to the identification, formulation and implementation of amendments to the clinical protocol, in close collaboration with clinical lead.
  • Contribute to the creation of study-level documents, including preparation of clinical sections of key regulatory documents, such as Investigator’s Brochures, briefing books, safety updates and submission dossiers.  Contribute to the review and writing of clinical trial documents for CTR activities, and publications (if applicable).
  • Support pharmacovigilance activities (e.g. contributing to aggregate reports, patient narratives, attendance of pharmacovigilance monitoring meetings)
  • Support regulatory activities, like preparation of meetings with regulatory agencies.
  • Produce training materials, share best practices and provide training to the broader clinical trial teams.
  • Support preparation and (if applicable) participate in study level meetings for example Investigator Meetings, Data Monitoring meetings, and others.
  • Supports and guides the development of data review strategy, ensuring that protocol-level deviations, eligibility criteria, study assessments & other aspects of the protocol are implemented consistently across the study (across countries/ sites). This could also include support for Case Report Form (CRF) development, and implementation of data capture tools.
  • Perform high quality clinical data review and identify clinical data insights through ongoing patient level review and trends analysis, thereby supporting for example Interim Analysis, Database and Post Lock activities and resolution of scientific & medical issues throughout the study lifecycle.
  • Work to improve the quality of reviews/ insights with an emphasis on subject safety and eligibility, data integrity, trend identification, analysis and remediation, and identification of cases for medical review.
  • Provide insights to and facilitate data review process improvements, for example by identification of redundant reports, implementation of innovative data analysis processes and tools, and their continuous improvement.
  • For all these tasks, work in close collaboration and alignment with clinical development lead. Ensure all questions / issues requiring medical oversight are brought to the attention of the clinical development lead.



  • Advanced degree in life sciences/ healthcare (or clinically relevant degree) is required.
  • Master’s, PharmD, MPharm, PhD, MBBS, BDS, MD strongly preferred.
  • 3+ years as a Clinical Trial Scientist or comparable role
  • Strong familiarization with Good Clinical Practice (GCP) and drug development processes, ideally Phase 1 – 3; ideally paired with experience in Oncology / Immuno-Oncology  
  • Good knowledge of set-up, organization and execution of global clinical studies in a pharmaceutical company or contract research organization (CRO), or comparable experience within academic research institution.
  • Sound knowledge of principles of clinical data collection and reporting; demonstrated ability to use systems and tools (e.g., EDC systems, Excel, etc.) for data collection, analysis and reporting. Ideally first experiences in how to improve and accelerate processes, systems and tools and drive continuous improvement.
  • Experience in RDC is an advantage.
  • Experience to work in a matrix, ability to influence without authority
  • High flexibility and adaptive working style, ability to work on several tasks at the same time
  • Ability to work effectively under high time pressure, while maintaining high quality standards
  • Ability to effectively prioritize tasks, and implement accordingly
  • High proficiency in English (written and spoken); German a plus

Benefits for you. 

BioNTech US is committed to the well being of our team members and offers a variety of benefits supporting our diverse employee base. Salaried/Position-Targeted Hourly Employees working 30+ hours per week are eligible for our comprehensive benefits package. Benefits include but are not limited to:

  • Medical, Dental and Vision Insurance

  • Life, AD&D, STD and LTD Insurance

  • HSA & FSA Spending Accounts

  • Health & Wellness, including free onsite gym access

  • Adoption & Surrogacy Assistance

  • Vacation and Unlimited Sick Time

  • Holidays and Floating Holidays, including discretionary winter shutdown

  • 401(K) Plan with Significant Company Match

  • Tuition Reimbursement and Professional Development

  • Commuting Assistance and subsidized parking

  • Discounted Home and Auto Insurance

  • Pet Insurance

Plus more benefits that will be shared upon hire!


Have we kindled your pioneering spirit? 

Then apply now for our location Cambridge (Boston) and simply send us your application documents using our online form. #LI-DCA

*BioNTech does not differentiate on the basis of gender, political opinion, religion or belief, nationality, ethnic or social origin, age, sexual orientation, marital status, disability, physical appearance, health status or any other aspect of personal status. We are committed to creating a diverse and inclusive environment and are proud to be an equal opportunity employer. Most important – it’s a match!

BioNTech - As unique as you